ABSTRACT
Schistosomiasis is the most common problem in Gezira area. The prevalence among school children could reach up to 90% in some villages. This study was conducted in a small village in the Gezira area in central Sudan. This part of the Gezira is well known for its high endemicity of Bilharzia. A total of 428 individuals were included in the study. All were examined clinically and by Ultrasoungraphy for spleen and liver. Stoll specimens were also taken from all the subjects and were examined for Schistosoma mansoni ova. The prevalence of schistosomasis was found to be 72% in males and 68 3% in females. It was also observed that the overall prevalence of splenomegaly on the examined subjects was 35.8%. Males recorded higher prevalence of splenomegaly [38.8%] compared to females [32.7%] [p =/< 0.05]. The observed prevalence of hepatomegaly was 12.6%., with high prevalence among males [13.1%] compared to females [11.2%]. Out of the 406 subjects examined by ultrasound, 266 [63.1%] were found to have evidence of periportal fibrosis. The hepatomegaly in the different grades1.2 and 3 are 12.6%, 3.8% and 0% respectively. It is clear from the above data that the size of the spleen increases while the size of the liver decreases with the severity of periportal fibrosis